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Lean, Mean Information Machine: Using a Simple Model to Learn about Chromosomal DNA
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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.
DNA Modeling Activity
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Using pipe cleaners, straws, and beads, learners explore the building blocks of life by creating their own model of DNA.
Life Size: What's in a microbe?
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In this activity on page 3 of the PDF, learners visualize the relative size and structural differences between microbes that have the potential to cause disease.
Yummy Gummy Double Helix
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In this activity, learners make their own edible DNA double helix out of candy and find out about the shape of DNA.
Gel Electrophoresis
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In this activity, learners simulate the process of DNA fingerprinting by using electricity to separate colored dyes.
Inside DNA
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In this activity (on pages 34-39), learners make a fairly detailed model of DNA using licorice and gumdrops.
Biobarcodes: Antibodies and Nanosensors
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In this activity/demo, learners investigate biobarcodes, a nanomedical technology that allows for massively parallel testing that can assist with disease diagnosis.
Macromodel of Microarray
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This is an educator-led demonstration of microarray technology using a model created from a pizza box and ping-pong balls.
Make a DNA Model
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In this activity, learners make a 3-D model of DNA using paper and toothpicks. While constructing this model, learners will explore the composition and structure of DNA.
DNA Jewelry Models
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In this activity, learners construct a model of DNA to better understand the structure of DNA and protein synthesis.
Origami DNA
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In this activity, learners create an origami model of DNA, demonstrating its double helix structure.
Make Your Own DNA
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Learners match puzzle pieces to outlines of a DNA strand. The puzzle pieces represent the four chemicals making up DNA base pairs: adenine, thymine, guanine, and cytosine.
Breakfast Proteins
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In this activity, learners construct a cereal chain as a model of how proteins are made in the cell.
Reading DNA
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In this activity, learners use edible models of the DNA molecule to transcribe an mRNA sequence, and then translate it into a protein.
Have Your DNA and Eat It Too
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In this activity, learners build edible models of DNA, while learning basic DNA structure and the rules of base pairing.
The Ladder of Life
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In this activity, learners identify the DNA base bars guanine, cytosine, thymine and adenine. Learners create a DNA model using colored paper clips to resemble these base pairs.
Born of Blood: Craft Stick Chromosomes
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In this activity, learners work in groups to match craft sticks that represent chromosomes. Learners must define critical attributes of their chromosomes as they look for matching chromosomes.
Self-Assembly Game
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This is a quick game about self-assembly (page 2 of PDF under Self-Assembly Activity). Like the molecules of DNA, learners will self-assemble into a pattern by following a simple set of rules.