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The Geophysical Light/Dark Cycle
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This is an activity (located on page 131 of the PDF) related to sleep and circadian rhythms as well as space travel.

Feel the Heat
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In this design challenge activity, learners design and build a solar hot water heater. Their goal is to create a heater that yields the highest temperature change.

How Long Can You Hold Your Breath?
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In this activity (on page 142 of the PDF), learners will compare breathing rates before and after hyperventilation to explore how reduced carbon dioxide levels in the blood lower the need to breathe.

Pitch, Roll and Yaw: The Three Axes of Rotation
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In this activity (page 87 of the PDF), learners move their bodies to better understand the three axes of rotation: pitch, roll and yaw.

Changing Body Positions: How Does the Circulatory System Adjust?
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In this activity about how the body regulates blood pressure (page 117 of the PDF), learners make and compare measurements of heart rate and blood pressure from three body positions: sitting, standing

Building a Magic Carpet
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In this activity (page 89 of the PDF), learners compare and contrast pitch and roll motions by using a Magic Carpet maze similar to one that was used for Neurolab investigations about microgravity.

Measuring Blood Pressure in Space
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In this activity (page 105 of the PDF), learners measure heart rate and blood pressure and learn how to obtain consistent measurements during repeated tests.

Building a 3-D Space Maze: Escher Staircase
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In this activity (page 95 of the PDF), learners create Escher Staircase models similar to those that were used by Neurolab's Spatial Orientation Team to investigate the processing of information about
Butterflies in Space
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The Butterflies in Space Teacher's Guide uses "life in space" to encourage learners to conduct their own open-ended scientific investigations.
Bag of Bones
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In this activity, learners will use cereal to conduct an experiment and investigate how decreased bone density is related to increased risk of bone fracture.