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How Big is Small
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In this classic hands-on activity, learners estimate the length of a molecule by floating a fatty acid (oleic acid) on water.

Lima Bean Bacteria DNA Extraction
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This laboratory exercise is designed to show learners how DNA can easily be extracted from lima bean bacteria. This experiment requires the use of a centrifuge (not included in cost of materials).

Having a Gas with Cola
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In this activity, learners measure the amount of carbon dioxide in a carbonated drink.

Fruit Xylophone: Fruit Salad Instrument of the Future!
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This is a perfect summertime lunch activity! Pico Cricket is required (micro controller). First, get a bunch of cut up fruit, line them up, then plug a piece of fruit with a Pico Cricket sensor clip.

Thymus DNA Extractions
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This laboratory exercise is designed to show learners how DNA can be extracted from a chunk of thymus (sweetbread) or liver.

Energy Choices Board Game
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This board game teaches learners about energy decision making. Players select cards that determine the transportation and home design that will influence their expenses as they play.

Exercise in Creating Drawings for Field Notebooks
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Learners draw and describe a leaf, and then re-find leaves drawn and described by other learners. Learners can observe leaves outside, or leaves may be brought into the classroom.

Supermarket Science: The King Sooper Lab
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In this investigation, learners gather information on various food items during a field trip to a local grocery store.

Swell Homes
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In this outdoor activity, learners find the swollen bumps known as "galls" on various plants and get a closeup look at the parasitic animals living inside.

Portable Potable Pressure
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In this activity, learners use plastic water bottles, wood, and water to build an inexpensive and portable tool to demonstrate one atmosphere of pressure at sea level.

Paperfolding Polyhedrons
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In this activity (on pages 55-66 of PDF), learners fold paper into origami shapes and then combine several identical shapes into a three-dimensional structure.

What's the Matter
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In this activity, learners identify different classes of matter based on physical properties.

Exploring the Nanoworld with LEGO Bricks: Structures and Their Construction at the Nanoscale
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In this activity (pages 42-49), learners discover the methods and challenges of building nanoscale structures with macroscale equipment.

Reading DNA
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In this activity, learners use edible models of the DNA molecule to transcribe an mRNA sequence, and then translate it into a protein.

DNA and Histone Model
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In this activity, learners construct a 3-D paper model depicting how histone, acetyl and methyl molecules control access to DNA and affect gene DNA expression.

Rutherford's Enlarged: A Content-Embedded Activity to Teach about Nature of Science
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This paper describes a working-model demonstration of Ernest Rutherford's 1911 experiment about the nature of atoms.

Make a Comet Model and Eat It!
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In this activity, learners build models of comets, using edible materials, to learn about comets' structure.

Have Your DNA and Eat It Too
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In this activity, learners build edible models of DNA, while learning basic DNA structure and the rules of base pairing.

Don't Throw it in the Garbage
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In this activity, learners discover why only some types of plastic can be recycled.

Exploring the Nanoworld with LEGO Bricks: Structure-Property Relationships at the Nanoscale
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In this activity (pages 32-41), learners learn how the atomic and molecular arrangement of matter are related to physical properties.