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In this activity, learners use information gathered from a variety of sources to design and make their own insect.

In this activity (on pages 26-33), learners play parasitologists, solving several "mysteries" about people who got sick from various parasites. In teams of four, each member solves one mystery.

In this simulation of synapses, learners act out communication at the neural level by behaving as pre-synaptic vesicles, neurotransmitters, post-synaptic receptors, secondary messengers and re-uptake

In this matching game, learners study the limits of life on Earth to see what other places in the solar system might sustain microbial life.

In this activity about neuron/target muscle recognition (page 44 of the PDF), learners arranged in two rows facing away from each other use string to simulate neural development.

In this activity about humans and space travel (page 1 of PDF), learners compare and contrast the behavior of a water-filled plastic bag, both outside and inside of a container of water.

In this graphing exercise (page 2 of the pdf), learners compare their own height to the length of various sharks.

In this simulation activity, learners will raise a pack of wolves under ten different conditions: without human interference and with human interference.

In this activity (on page 1), learners role play as atoms to explore how atoms can be rearranged to make different materials.

In this classic memory game (on pages 37-45 of PDF), learners turn over tiles to reveal images on the back.

In this activity, some learners pretend to be wolves, while the other learners pretend to be the prey of the wolf. The goal of the simulation is to have the wolves work together to survive.

Learners observe the outside and inside of raw chicken eggs, record descriptions, and hypothesize what will happen when a facilitator drops an egg on the floor.

In this inquiry-based activity, learners investigate the basic forces of flight as they construct their own paper glider that represents a rainforest creature from Borneo (large, tropical island in So

Learners will build a homemade pump using a balloon, a mason jar, and some straws.

In this activity, learners examine the culture and history of the tomb site.

This exercise can be used to stimulate the investigative nature of learners as they use forensic plant pathology techniques to prove the learners' innocence in a mock murder investigation.

In this "gross" activity (on pages 34-46), learners make a life-size model of a human digestive tract, and follow the life of a beef tapeworm as it makes its way through.

In this activity (on page 142 of the PDF), learners will compare breathing rates before and after hyperventilation to explore how reduced carbon dioxide levels in the blood lower the need to breathe.

This activity focuses on interactions within Earth systems and the effects of human activities. In this activity learners build a biomass pyramid.

In this interactive board game, learners "hire" different types of scientists to help canine character Ruff Ruffman solve unusual problems.